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I may be wrong but the majority of the Pathfinder APs seem to be about returning things to the status quo (or some semblance of it) as at the start of the adventure.
There are some adventure paths that fit into that category, but some which also change the status quo by the end. Kingmaker, Jade Regent, Wrath of the Righteous, and Hell's Rebels stand out to me as adventure paths where the world is potentially very different by the end of the campaign.
The trick is that none of the adventure paths' potential endings become mentioned as definite things that happened in later supplements. I imagine an adventure path where you defeat Razmir would be the same - just because he's gone in that campaign doesn't mean he's gone from Golarion.