Hmmmm, now I know what the editorial department will be doing for Thanksgiving!
That is a beautifully ambiguous statement. :)
You want clones? I can help. A few million in startup funds for my own biotech firm, some denucleated cow eggs, and a small tissue sample and we're in business for letting you eat your very own clone. But of course since we'll be making your clones all sciencey and grown in vats rather than the normal way, I can already tell you that you'll taste like beef. All the gallons of fetal bovine serum we'll go through will leave an aftertaste, or at least a residue.
... what?
Too...
Much...
Info...
No way. Tell us more, Todd. Slowly... :)
Hmmmm, now I know what the editorial department will be doing for Thanksgiving!-Lisa
Whoa. Our fearless leader ladies and gentlemen!
I'll take your clone and Sutter's. Just contact me for shipping information. I swear they will be treated well.
Uh. Whoa. Um. Thanks? 0_o
What an innovative and diabolic attitude. >;-)
That reminds me of this comic strip.
Oh how I loved PLIF.
I'll take your clone and Sutter's.
Two great tastes that taste great together?
Two great tastes that taste great together?
Wow. There's just noting that I can write here that doesn't sound filthy. So. Um. OUT.
|
Uh. Whoa. Um. Thanks? 0_o
You're welcome.
Though I didn't mean to creep you out or anything. :) I just figured clones could be put to better use than cannibalization.
Ummm....yeah....awkward and creepy when I think about it that way.
Sorry about that.
On that note, I am off to the store to buy Gods and Magic.
That will make it all better.
Two great tastes that taste great together?
I'll take your clone and Sutter's.
That's the problem with clones. You can't eat just one.
The Tears of a Clone.
|
I'm still looking forward to Sean's novella "The Sexy Secret of Saltmarsh." Get over here you sexy lizardmen. Rowr.Somebody, better quickly tell him that the cloaca is not an OGL monster...you want this...Now I'm wishing Vomit Guy was my alter ego.
*turns shades of green*
You leave Vomit Guy out of this. He's living a happy life-in-exile over in the Off Topic section.
Sploooortch!
Did I hear cloning?
Such a waste of potential. When you're making replicas, try to improve them. You're cooking up something new, anyway, why go right where nature went wrong?
Auto-cannibalisation hasn't occured to me yet, but my research into flavour-altering GM should work well here. What do you want to taste like today?
|
You want clones? I can help. A few million in startup funds for my own biotech firm, some denucleated cow eggs, and a small tissue sample and we're in business for letting you eat your very own clone. But of course since we'll be making your clones all sciencey and grown in vats rather than the normal way, I can already tell you that you'll taste like beef. All the gallons of fetal bovine serum we'll go through will leave an aftertaste, or at least a residue.
... what?
Can't we start with stuff like the Moa birds? I'm pretty sure we can find viable DNA sources since they only died out a few centuries ago and they only went extinct from man hunting them to death. Not to mention a 10' tall chicken would rock as a foodsource.
Ah. The Moa. Hunted into extinction for being too tasty.
Yes. Bring it back.
And once you do that, you can get started on Boosterspice and the other Known Space geneotech.
Creative Director
|
Danger!
I've seen chickens do their thing. We had chickens growing up. Chickens will eat anything. The reason they don't eat people is because people are too big. But still, I've seen ill-tempered chickens (roosters, mostly) go after people before. They've got the exact wrong combination of stupid and angry and talons.
A ten foot tall chicken?
I repeat: DANGER!!
Danger!
I've seen chickens do their thing. We had chickens growing up. Chickens will eat anything. The reason they don't eat people is because people are too big. But still, I've seen ill-tempered chickens (roosters, mostly) go after people before. They've got the exact wrong combination of stupid and angry and talons.
A ten foot tall chicken?
I repeat: DANGER!!
James has the right of it. We have a 9" tall bantam that tries to attack anything that moves. It's either trying to kill it or breed with it. Crazy little sucker.
A 10' tall version of him? No thanks.
Danger!
I've seen chickens do their thing. We had chickens growing up. Chickens will eat anything. The reason they don't eat people is because people are too big. But still, I've seen ill-tempered chickens (roosters, mostly) go after people before. They've got the exact wrong combination of stupid and angry and talons.
A ten foot tall chicken?
I repeat: DANGER!!
Excellent. I shall unextinct them through cloning, harden their talons, heighten their anger, and add something so they can be controlled by something that will be a closely guarded secret, so they can serve as mounts.
With such a beast, I shall be able to take over the world!
I'll also breed them much larger, to serve as mobile siege towers and mounts for my runelords. The sight of 40-foot-tall giants mounted on 60-foot-tall roosters shall inspire sheer terror in my enemies.
James has the right of it. We have a 9" tall bantam that tries to attack anything that moves. It's either trying to kill it or breed with it. Crazy little sucker.
I hope you call him Greebo. Or at least Legba.
Alright. So skip the Moa.
I still want Boosterspice.
|
Contributor
|
You want clones? I can help. A few million in startup funds for my own biotech firm, some denucleated cow eggs, and a small tissue sample and we're in business for letting you eat your very own clone. But of course since we'll be making your clones all sciencey and grown in vats rather than the normal way, I can already tell you that you'll taste like beef. All the gallons of fetal bovine serum we'll go through will leave an aftertaste, or at least a residue.
... what?
Nice- we went from horsey sauce to um...cowboys.
By the way Todd, what are you using to denucleate the eggs, I've been running into a few complications using uv light. Is there a way to concentrate it directly on the nucleus?
Nice- we went from horsey sauce to um...cowboys.By the way Todd, what are you using to denucleate the eggs, I've been running into a few complications using uv light. Is there a way to concentrate it directly on the nucleus?
Conceptually I'm familiar with a few methods, though in practice I've never done work related to cloning w/ somatic cell nuclear transfer to recipient oocytes. There are some methods of cetrifugation with a percoll gradient that can strip out chromosomal material, though I suspect there would be considerable loss of viable cells along the way, having used such spin techniques on other cell lines for purification purposes (hepatocytes mostly, and some other gradients for spinning down pancreatic islets).
There's always physically stripping out the chromatin, and treating the cell with cytochalasin B to maintain integrity, but that's horribly tricky, and it's one at a time and I don't have that level of patience when planning on creating an army of evil clones. Then there's treatment with etoposide which prevents chromatin segregation at metaphase 1, and dumps the whole lot of it as a polar body. Again I'm not familiar enough with the procedure to say what the yield would be without actually researching the procedure a bit more.
*cough* And at some point there would be some tricky rolls involved, because some of those skills are only cross-class for me given my PrC I've gone into since grad school.
By the way Todd, what are you using to denucleate the eggs, I've been running into a few complications using uv light. Is there a way to concentrate it directly on the nucleus?
Conceptually I'm familiar with a few methods...
This is a drunken conversation I want to hear next Gen Con.
|
|
Danger!
I've seen chickens do their thing. We had chickens growing up. Chickens will eat anything. The reason they don't eat people is because people are too big. But still, I've seen ill-tempered chickens (roosters, mostly) go after people before. They've got the exact wrong combination of stupid and angry and talons.
A ten foot tall chicken?
I repeat: DANGER!!
Mmmmm.....Popeye's Fried Chicken.
I've seen chickens do their thing. We had chickens growing up. Chickens will eat anything. The reason they don't eat people is because people are too big. But still, I've seen ill-tempered chickens (roosters, mostly) go after people before.
A chicken tried to eat my little brothers toe once.
Though in fairness the only farm animal that hasn't tried to kill me is a pig, and I'm including ducks! And we don't have pigs, OR ducks at home.
Dire Farmyard animals would be pretty damn scary...
Danger!
I've seen chickens do their thing. We had chickens growing up. Chickens will eat anything. The reason they don't eat people is because people are too big. But still, I've seen ill-tempered chickens (roosters, mostly) go after people before. They've got the exact wrong combination of stupid and angry and talons.
A ten foot tall chicken?
I repeat: DANGER!!
Isn't a ten-foot chicken pretty much a raptor with a beak? Just sayin ...
By the way Todd, what are you using to denucleate the eggs, I've been running into a few complications using uv light. Is there a way to concentrate it directly on the nucleus?This is a drunken conversation I want to hear next Gen Con.
Conceptually I'm familiar with a few methods...
I'll have to scratch together some money and attend, then.
I'll have to scratch together some money and attend, then.
By the way Todd, what are you using to denucleate the eggs, I've been running into a few complications using uv light. Is there a way to concentrate it directly on the nucleus?This is a drunken conversation I want to hear next Gen Con.
Conceptually I'm familiar with a few methods...
Nah, it'll just devolve into a 'my beta-protein/nuclear whatsit is bigger than yours' argument. Then the rubber gloves get whipped out and all hell breaks loose.
Hey, on second hand...
This is a drunken conversation I want to hear next Gen Con.
Me too! :D
ha HA! Now Jason's the one on the hot seat being interviewed! Too bad you're not here in the office to harass him, Wes. You missed out!
You know, these are the times when you need an electronic fart maker.
Nice- we went from horsey sauce to um...cowboys.By the way Todd, what are you using to denucleate the eggs, I've been running into a few complications using uv light. Is there a way to concentrate it directly on the nucleus?
Conceptually I'm familiar with a few methods, though in practice I've never done work related to cloning w/ somatic cell nuclear transfer to recipient oocytes. There are some methods of cetrifugation with a percoll gradient that can strip out chromosomal material, though I suspect there would be considerable loss of viable cells along the way, having used such spin techniques on other cell lines for purification purposes (hepatocytes mostly, and some other gradients for spinning down pancreatic islets).
There's always physically stripping out the chromatin, and treating the cell with cytochalasin B to maintain integrity, but that's horribly tricky, and it's one at a time and I don't have that level of patience when planning on creating an army of evil clones. Then there's treatment with etoposide which prevents chromatin segregation at metaphase 1, and dumps the whole lot of it as a polar body. Again I'm not familiar enough with the procedure to say what the yield would be without actually researching the procedure a bit more.
*cough* And at some point there would be some tricky rolls involved, because some of those skills are only cross-class for me given my PrC I've gone into since grad school.
Todd, what DID you go to school for? Genetics? Molecular Biology? Or just straight Chemistry or Biology?
|
Danger!
I've seen chickens do their thing. We had chickens growing up. Chickens will eat anything. The reason they don't eat people is because people are too big. But still, I've seen ill-tempered chickens (roosters, mostly) go after people before. They've got the exact wrong combination of stupid and angry and talons.
A ten foot tall chicken?
I repeat: DANGER!!
I can vouch for this after almost getting mauled by a rooster when I was 5 I can still hear it Cawing...... WHY WONT IT STOP???? *Begins rocking back and forth in his chair*
Hey, on second hand...
Exactly:
Mad science debates: Good.All hells breaking loose: Better.
...
Profit!
We need to find out what to put where the dots are now. Get the movie rights maybe? I'm sure Tarantino would direct it, too!
You know, these are the times when you need an electronic fart maker.
Or the right lunch.
Todd, what DID you go to school for? Genetics? Molecular Biology? Or just straight Chemistry or Biology?
That's in the standard curriculum for Bachelor in Villainy. You don't want to know what the Master's curriculum includes...
Todd, what DID you go to school for? Genetics? Molecular Biology? Or just straight Chemistry or Biology?
BS Chem and BS Bio undergrad. MS Bio in grad school, and I'm kicking myself for not spending an extra two years for the PhD, because it's going to be hard as hell pushing myself to go back for it and endure another stint of voluntary poverty.
Grad school was focused on a mix of Cell Bio and Immunology, and most of my work since graduation has been in those areas as well, with the cell bio itself focused on stem cells and primary cell lines. Genetics is a real soft point for me, but otherwise I've really been all over the map. I slipped up the other day in the lab, talking to my boss about updating my resume to cover my current position, and I swear, I almost used "cross class skills" rather than saying "cross trained" between a few groups in the company.
But back on topic, as I understand it, chickens still have genes that code for them having teeth, they're just never expressed except in freaky cases. 10 foot tall chickens, with teeth. Better than any guard dogs. :)
|
Creative Director
|
But back on topic, as I understand it, chickens still have genes that code for them having teeth, they're just never expressed except in freaky cases. 10 foot tall chickens, with teeth. Better than any guard dogs. :)
woah
Teeth like a dinosuar? Teeth like a person? Teeth like a shark? None of the options will help me sleep at night.
|
|
But back on topic, as I understand it, chickens still have genes that code for them having teeth, they're just never expressed except in freaky cases. 10 foot tall chickens, with teeth. Better than any guard dogs. :)woah
Teeth like a dinosuar? Teeth like a person? Teeth like a shark? None of the options will help me sleep at night.
i think its like dinosaurs...
i remember a flying dinosaur with feathers... don't remember the name|
Contributor, RPG Superstar 2008 Top 6
|
i think its like dinosaurs...
i remember a flying dinosaur with feathers... don't remember the name
Sounds like the famous archaeopteryx to me. Not to be confused with the apteryx, a wingless bird with hairy feathers. (a little BC reference for the old folks)