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As a general rule the same effect doesn't stack with itself, so I'd assume that you stay switched.
This is of course assuming that the two items use what is essentially the same effect - given that changing gender isn't a spell at all it's probably up to GM interpretation whether this is the case or not.

Meirril |
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When this magical belt is put on, the wearer must immediately make a DC 20 Fortitude saving throw or be transformed into a person of the opposite gender. The character’s abilities, mind, and spirit remain unaffected; only the character’s sex changes. If the character’s saving throw is a natural 1, the item actually removes all gender from the wearer, giving him an androgynous, neutered appearance. The change is permanent unless undone with curse-removing magic. Once its magic takes effect, the belt can be removed without effort. A creature can only be affected by a particular girdle once, though other girdles of this type can cause another transformation.
The girdle puts you under a curse. Which would result in you permanently switching genders, or becoming neutered. When you wear the belt, you would flip again until its removed since it seems to only work when you are wearing it.
Since it doesn't matter how long you've been wearing the belt (no benefit from the str bonus being permanent, it isn't a casting stat) why not just remove it when you are in civilized lands? Only wear the belt when you expect trouble. You could even leave the belt in an accessible container (like a pouch) and put it on as a standard action during combat. If you wore a veil or mask it would even make a semi-effective disguise. Well, not really, the gear looks exactly the same.
Oh, or you could spend 1000gp on a hat of disguise and make yourself look like your original gender. You could even make yourself look like you are wearing different gear.

zza ni |

Girdle of Opposite Gender wrote:When this magical belt is put on, the wearer must immediately make a DC 20 Fortitude saving throw or be transformed into a person of the opposite gender. The character’s abilities, mind, and spirit remain unaffected; only the character’s sex changes. If the character’s saving throw is a natural 1, the item actually removes all gender from the wearer, giving him an androgynous, neutered appearance. The change is permanent unless undone with curse-removing magic. Once its magic takes effect, the belt can be removed without effort. A creature can only be affected by a particular girdle once, though other girdles of this type can cause another transformation.The girdle puts you under a curse. Which would result in you permanently switching genders, or becoming neutered. When you wear the belt, you would flip again until its removed since it seems to only work when you are wearing it.
Since it doesn't matter how long you've been wearing the belt (no benefit from the str bonus being permanent, it isn't a casting stat) why not just remove it when you are in civilized lands? Only wear the belt when you expect trouble. You could even leave the belt in an accessible container (like a pouch) and put it on as a standard action during combat. If you wore a veil or mask it would even make a semi-effective disguise. Well, not really, the gear looks exactly the same.
Oh, or you could spend 1000gp on a hat of disguise and make yourself look like your original gender. You could even make yourself look like you are wearing different gear.
removing the normal sex change belt doesn't restore the sex back. once worn it change the sex immediately once. after which even if you remove or wear it again you stay the same. (unless you saved the first time, in which case you need to save each time you wear it again until you fail).
as for the OP. if you can get a 2nd cursed belt. wear it .remove it then wear this one. and if you save just remove and wear again until you fail.
hack. since it's magic still work i had an npc who RENT his cursed belt to misfortune people who got hit with a curse or WANTED to change their sex from the beginning.

Dave Justus |
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Having the girdle be a cursed item is kind of a weird legacy thing.
It certainly comes from a different age. But I think the concept is still valid. Not having your biology match your gender is a difficult thing, many would indeed say a curse.
If written "a person who identifies as male will become biologically female and a person who identifies as female will become biologically male" it would be perfectly valid as a cursed item and more in line with modern views of gender.

David knott 242 |

One issue here is that most things that switch your gender do so instantly, so the question of how to combine them never comes up.
But if you obtain and use one of those items that switches your gender instantly, then that would solve your problem. You drink the elixir or put on the cursed belt and switch your gender to the opposite of what you actually want. Then you put on your GM's special belt and you are the opposite (in this case, original) sex from what the other item switched you to as long as you are wearing it.

Dasrak |
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PossibleCabbage wrote:Having the girdle be a cursed item is kind of a weird legacy thing.It certainly comes from a different age. But I think the concept is still valid. Not having your biology match your gender is a difficult thing, many would indeed say a curse.
It's cursed in the sense that it imparts the change whether you want it or not, and is not easy to reverse. There are plenty of examples of things that are nominally curse effects, but may be desirable in some circumstances or to some characters. If there's a problem here it's that transgender people have been historically marginalized and ridiculed. This item treads very close to those crass tropes.

ErichAD |

What exactly does it change? Is it altering sexual characteristics or is it altering the language people use when referring to you and their reaction toward you based on their gender expectations?
In the first case, you should be able to forestall the change with an earlier polymorph effect. Just alter self to your own race and sex and that should block the new polymorph from happening. If it's the second case, I think you're stuck.

shadowskinC |
Perhaps the Anderos salve and mulibrous tincture will help in such situation. But I'm not sure which version you need. If that's something to be discussed, then Elixir of Sex Shift will definitely work.

Dasrak |

What exactly does it change? Is it altering sexual characteristics or is it altering the language people use when referring to you and their reaction toward you based on their gender expectations?
It's not specific about what's happening "under the hood" so to speak, but given the context and how it's traditionally been depicted I interpret it to mean changing all sexual characteristics and not strictly gender. Given that most people don't know the difference between sex and gender to begin with I wouldn't read too deeply into its word choice.
In the first case, you should be able to forestall the change with an earlier polymorph effect. Just alter self to your own race and sex and that should block the new polymorph from happening. If it's the second case, I think you're stuck.
It's not specifically called out as a polymorph effect, although that does open up a can of worms in other respects. For instance, is someone who drank an Elixir of Sex Shift subsequently immune to all polymorph effects (since they're under the effect of a permanent undispellable one?). Definitely something that a GM needs to think carefully about when ruling.

David knott 242 |

ErichAD wrote:What exactly does it change? Is it altering sexual characteristics or is it altering the language people use when referring to you and their reaction toward you based on their gender expectations?It's not specific about what's happening "under the hood" so to speak, but given the context and how it's traditionally been depicted I interpret it to mean changing all sexual characteristics and not strictly gender. Given that most people don't know the difference between sex and gender to begin with I wouldn't read too deeply into its word choice.
ErichAD wrote:In the first case, you should be able to forestall the change with an earlier polymorph effect. Just alter self to your own race and sex and that should block the new polymorph from happening. If it's the second case, I think you're stuck.It's not specifically called out as a polymorph effect, although that does open up a can of worms in other respects. For instance, is someone who drank an Elixir of Sex Shift subsequently immune to all polymorph effects (since they're under the effect of a permanent undispellable one?). Definitely something that a GM needs to think carefully about when ruling.
It isn't a polymorph effect -- it is an actual permanent physical change, similar to Reincarnation. After you consume an Elixir of Sex Shift and accept its effect, your physical sexual characteristics instantly change to the opposite sex. From that point on, your body is naturally and permanently that sex unless similar magic is used to switch your physical sex again. Since you are not under a polymorph effect at that point (or, indeed, any other magical effect), polymorph spells and effects would work normally on you. When they expire, you would revert to your latest permanent form.