Considering that 1 in 10,000 men and 1 in 30,000 women (an estimate by the Amsterdam Gender Dysphoria Clinic) seek sexual reassignment there should be at least one in a large city in D&D and several in a metropolis. It may not be for everyone, but I think this kind of background is interesting, both from a role playing and immersion perspective.
I seem to recall a cursed magical item called the girdle of femmininity/masculinity that magically switches a character's gender. That would be a boon for folks wanting gender reassignment.
And drow are into SM? Hm, Verik married a drow at the end of his career, no wonder he's happy... ;)
"You think being a god is tough? Try raising my three kids." -Verik Wolf.
I saw the Rage Points and thought, oooo. It's an interesting way to keep barbarians fun while not making them just another fighter variant. Plus, when I rebuilt my old AD&D character to use Pathfinder, the combination of 3.5 psionics and Pathfinder Rage Points meshed well. From a compatibility standpoint maybe they're not the best, but that could be solved by turning the rage powers into barbarian specific feats and selecting one as he/she levels up.
I just rebuilt an old barbarian character of mine into Pathfinder Alpha 2, and I like the skill system. I didn't see the Alpha 1 system so I cannot comment, but not having to track half-skill ranks is a nice change. If Paizo is gearing for backwards compatibility then the new skill system is good for that. Perhaps a way to convert rank-based skills to the Alpha 1 system would appeal to both parties while retaining the system's goal of compatibility.