My first PC death resulted when the party's Elf Alchemist decided that it would be a good idea to approach the Treasure Pit on his own. They broke through the cork, and lowered him down on a rope, which he promptly stated that he released when he hit water.
Given the circumstances (6 players) I had increased the number of Ghouls to 3. He was second level at the time, went to 3 in the surprise round and lost the initiative roll for the first round and died. The second PC I lost, the party's Gnome Summoner, survived the encounter, but contracted Ghoul Fever.
Shortly thereafter, the PCs made their way back to camp to pickup a replacement (I had allowed a few members of the crew/extra NPCs to survive the initial wreck after reading how deadly this adventure could be), and headed back out.
The Gnome Summoner, sadly, made both saves for the Ghoul Fever. 4 game days later the PCs had made it to the area where sacrifices are left for the RMD. They decided to spend the night in a nearby (appropriately placed) cave (which I explained as a small cave that was covered in bones/gore from previous sacrifices after them making a religion check). A random encounter resulted in 3 shocker lizards.
28 points of damage downed the Gnome summoner, while the rest took 14. The next blast from the lizards dealt 16 points of damage, killing the summoner and dropping 4 members of the party to negatives. The only person on his feet was the barbarian (who had replaced the elf alchemist), who took down the remaining 2 shocker lizards.
He remained holed up for 3 days (during which I did roll random encounters, of which 5 triggered- talk about bad luck!) With only the party's fighter waking up on day 2.
They ofc returned to camp, picked up a replacement, discovered that Aerys (who in 2 weeks of play had not made a single morale check) was missing, and went gungho into the jungle after her.
Arriving at the Cannibal camp they faced 14 cannibals plus Klorak, and the barbarian (who had protected them all while they were unconcious) was left after he fell to negatives and the rest fled.
He was then dumped into a stew pot (essentially blanched) then dumped out into the dirt and had his chest cracked open so Klorak could eat his heart and rub the barbarian's life blood upon his chest, and now is suspended over Klorak's "throne" so that his blood may rain down upon the chieftan (what little is left) and off they trek back to camp!