A year ago, I would have said no. But, from what I've seen so far, and against all odds, 5e looks like it will hit the sweet spot for me. So it's now a definite yes.
I will still spend money on PF materials such as pawns, and I might even continue using Golarion as our setting, but I can't see myself buying any more PF rules supplements.
I think that the best way to accommodate all play styles is to do exactly what they are doing now.
Start with a very light tactical game that incorporates the most iconic features of the various editions, then create modular rules and options for more character customization, tactical depth, alternate spellcasting systems and so forth.
It would be a lot more difficult to build the system the other way around.
That's sort of what happened with the 4e Essentials line. It was offered as a tactically lighter version of "core" 4e, with a nod to more traditional iconic elements, but it apparently satisfied very few people in either camp.
I can't blame Wizards for trying to get the horse before the cart this time.
Ideally, I prefer 4 or 5 players. 6 is okay as long as they are half-way organized. A party of 7 or 8 requires a lot of work and a lot of pressure to keep things moving quickly, but I've managed a campaign with those average numbers for about ten months now and it can be done. 9 is too darned many. Especially when they start bringing along their cohorts, undead minions and animal companions.