The Harrow Deck has a wide variety of uses, from a divination tool to a common game played for coppers in taprooms across Golarion. The game is known as Towers, and it is included in the Harrow Deck.
Towers is a simple gambling game for two to four players. At the start of the game, six special cards are laid out from the Harrow Deck, forming the base of the towers. Each player is dealt a hand of three cards. Players take turns placing cards from their hand onto the towers, trying to rid themselves of as many cards as possible while blocking the way for opponents to do the same. If you can't play some of your cards, they accrue as debt owed to the other players. As the game progresses it becomes harder and harder to play your cards and your debt can really spiral out of control. The game comes to an end when no one can play any more cards. At that point, each player's debt is tallied and players must pay the difference to those with a lower value.
The game is simple to learn, but has some complex strategy for those who are eager to fleece their opponents. A word of caution: This game can be addictive and I would hate to see someone lose a vorpal sword over a few bad hands.