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I have always found that static DCs that interact with NPC/Monsters that have no modifier for that creatures ability/Skills/Saves to be a broken concept.
Prime examples are:
Diplomacy
Arobatics(Tumble)
Concentration
Furbur Fuzzyfist, Halfling Rogue 7th level, Dex 18
Tumble Skill w/No Magic : Ranks(10) + Dex(4)
Cannot fail to successfully Tumble around any creature that exists and is only level 7, this occurs earlier with the application of magic and feats.
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With any of those skills after a certain level you can affect creatures from kobolds to dragons and beyond with little or no chance of failure. I would recommend that the DC be set to a set value then modified by the appropriate Ability Mod/Skill/Save to represent the interaction that is occuring. The creatures reflex could be kept secret so that the players choice to tumble is not purely based on math.
You are trying to prevent an attack of opportunity from movement, so it would seem easier to move around an ooze as compared to doing so to that multi-armed sword wielding demon.
Move through a threatened area : DC10 + Reflex Save of affected creature
Move through an enemy's space : DC20 + Reflex Save of affected creature
(Increase the DC by +2 for each opponent above one that threaten a particular location))
Example:
Furbur Fuzzyfist, Halfling Rogue 7th level, Dex 18
Acrobatic chosen for Trained Skill : 1d20 + 7 + 3 + 4
3 gargoyles that have dropped among his party of 4, he needs to get past them to unlock the door.
DC 20 : Base DC 10 + 6(Gargoyle Reflex) + 4(2 extra gargoyles)
Now the player has to make a decision about doing his chosen action.