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This is some serious b%%~!~@@. Spend some time on the internet and you'll see that, frankly a lot of people are into that, at least in theory.
Additionally, more people than have it as an interest might be able to muster some interest if the creature in question was a real person who they fell in love with. Some wouldn't, but it wouldn't be unheard of.
And finally, a lot of the creatures that have been discussed are shapechangers. Do you really care if the beautiful woman (or handsome man) you love happens to be able to turn into a snake or a spider, or whatever? I wouldn't.
A lot of people "on the internet" are into a lot of things, but I would argue that what one finds on the internet in regards to a great many things is still not normative. The internet simply allows obscure groups and subcultures to interact with relative ease. In the physical world, folks who have a borderline bestiality fetish are still very, very few and far between.
I stated that I could wrap my brain around romance between human and those who can take human form. I would just wonder why such a creature would find humans sexually attractive. I didn't say there was anything wrong with a fetish, I just think that such pairings would be very, very, very rare. That is unless monster/inhuman fetishists are common in Golarion.
Love? Really? I love my cat, but even if my cat started chatting with me like Puss n' Boots I'm not going to want a sexual relationship with him...1.) he's male and 2.) he's a cat....HE'S A TALKING CAT. Love is one thing, but the desire to be physically intimate with an individual is another often unrelated thing. I think it's a mistake to conflate the ability to love someone with the desire to have sex with someone. I could imagine loving a female gnoll as a dear friend but I wouldn't have sex with a even the sexiest gnoll female because the idea of such an encounter is unappealing...because she's a hyena person...with "hyena" being the operative word. She's a furry animal-person. Kissing is out of the question unless one thinks it arousing to kiss their family dog.
By the same token, I don't believe our sexy female gnoll would want to have sex with furless, unspotted, primate me. It just makes sense.
Again, there is nothing wrong with fetishes, but that is what we are talking about here...it's fetishistic to desire sexual congress with a "person" that bears an obvious combination of human and animal characteristics. That's not "wrong" but it would be, in any believable setting....very, very rare.