After spending way too many hours converting Shackled City to Golarion and PF, I've finally been able to run it. So far, it's going great, although it's taken some unexpected turns.
First off, I decided I wanted Vhalantru and Thifirane Rhiavadi to play bigger roles in the adventure. I made Lord Vhalantru in charge of Cauldron's adventuring licenses. No license means no adventuring, and to get a license requires the sponsorship of a noble house. Vhalantru was able to get Thifirane to agree to sponsor them (after the party took care of a nasty rat problem for her). The party didn't much like the arrogant Thifirane, but they seemed to like Vhalantru. Exactly the result for which I was hoping.
The party wisely explored all of Jzadirune before heading down to the Malachite Fortress, but unfortunately for them, they quickly found Kazmojen while still level 2. They started running when Kazmojen knocked Fario and Fellian unconscious with one attack each. The last person out saw Orbius teleport in, claim Terrem, and teleport back out.
After that mess, they decided to prepare more carefully, and perhaps explore the Malachite Fortress first. Seeing as how Kazmojen stomped them so thoroughly, I figured he wouldn't bother increasing the guard - the clearly incompetent adventurers were no threat to him.
The party found Fario and Fellian in the prison cells and rescued them, as well as the other slaves, and with careful preparation, stomped Kazmojen as easily as he did them the first time. Unfortunately, however, the remaining three children - Deakon, Lucinda, and Evelyn - were no where to be found, since after driving off the party the first time, Kazmojen finished the sale to the durzagon. I left a receipt on Kazmojen, however, stating the children were sold to "Pyllrak Shyraat, denizen of the Darklands."
My players weren't exactly keen on the idea of venturing into the Darklands until Jenya told them the reward was for rescuing the children. Still, they detoured off to Kingfisher Hollow to investigate...
After seven years my group is about to finish Shackled City. It is quite a journey. I suggest you spend some time in the early parts of the adventure foreshadowing Adimarchus as well as introducing some of the Cagewrights to the PCs. I had Freija Doorgan as the owner of the local magic shop, Ardeth Webb as the Mayor's bodyguard, Shebelith as dean of the academy, Fish as owner of a tavern, etc. It makes the later encounters much more interesting.