
Blave |
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It's not better or worse, just different.
Pros: Targets Reflex instead of Fortitude. Inflicts a -2 attack penalty on top of off-guard, so at least martial enemies are likely to waste an action standing up, which also trigger Reactive Strike and similar abilities.
Cons: Doesn't grapple. Immobilize is a harsh condition and getting rid of it doesn't only take an action (unlike prone) but will also affect the enemy's MAP. Grapple also potentially screws spellcasters.

Lia Wynn |

Also, Slither is not enemy only, so you may not get Reactive Strikes from allies when people stand up, since they likely do not want to be in the AoE themselves.
That said, Slither is a very good spell, and having an option to give it a variable effect would just make it better. Options do tend to be good to have.