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The Empiricist Investigator is an amazing skill monkey. I would suggest saving up for an impact weapon, because that is only a +1 enhancement. When you say twf with a bastard sword, do you mean two HANDED fighting? I'm assuming you are thinking of using a Large sized bastard sword like Amiri uses. And of course, Enlarge person is on the Alchemist list. Obviously, you will have take an attack to get the dutiful strike bonus. Are thinking of picking up Vital Strike at higher levels? I think it would be worth it...as you'll be doing something like 5d8 damage if everything lines up.
I think the downside of the sanctified slayer is that you are giving up judgements, which are very flexible; and the studied target is a movement action until level 7. You won't be able to Rapid shot on the same round that you are starting your studied target, whereas Judgements start off as swift actions. Also, the studied target increases the DCs of class abilities; I don't think it's clear that it would affect the DCs of your spells. So expect that some GMs might say that it doesn't work.
So for what its worth, my opinion is that the Empiricist/bloodrager would be a little better for what you're trying to do.
Effortless lace isn't PFS legal, and you can't get the inspired property on a bastard sword. Inspired is +1 equivalent and many investigators will want it.
Given the move action required to study a target, you might want to cast a standard action buff or debuff that round, or spend an action moving to a better position rather than shoot just once. It's not a show-stopper, just a change of tactics.
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Yes to furious. Investigator's study out scales slayer's especially with quick study. Consider accelerated driker. It will make your buffing routine crazy.
You should have long term buffs up, mutagen and heroism. Keep a potion in hand of enlarger person. Round one swift to study, move enlarge, standard other buff ( shield, combined extracts, polymorph etc.), free rage.
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Some people say you can't study it is a minority opinion as far as I can tell as it is not an int based skill and does not require concentration.
Drunken brute is fine. I have used it one an investigator build. But it's not compatible with armoured hulk so you can't get heavy armour, which you want on a strength investigator. Id rager also gives other really useful powers in place of rage powers (iron will, power attack, skill focus, accuracy and damage boosts). Some are only active while raging but are still great. I would say most rage powers or I'd rager power are worth way more than 2hp.
Weapons go 2 routes. An investigator weapon, short bow, long spear or rapier if you want inspired or best martial weapon if you don't want the inspired weapon enhancement. My recommendations are great sword, falcata, fauchard, or Lucerne hammer. With exotic weapon being picked up by picking up a Cracked Opalescent White Pyramid for 1500gp. A furious keen fauchard is amazing if you don't want to wait for improved criticals.
I love my Dex investigator but damage lags and you can use your best buff (monstrous physique well). I test ran mine with an unchained drunken brute and that work decently but your out of combat utility does suffer. Thought it is still a really fun character.
I have never done the math but I would think you lose a lot of damage potential on the vivsectionist using a single weapon one handed. Sneak build usually depend on lost of attacks or two handing and just considering the sneak damage bonus. I think the natural attack vivsectionist do really wallabies claw claw talon talon gore full Bab.