Suggestion for the Paizo team: get in touch with Scott McClintock and co over at Quill & Cauldron to see if they are open to doing a ' Doomed Golarion' in the style of the Doomed Forgotten Realms line they have released on the Dungeon Masters Guild.
Rise of Vecna
https://www.dmsguild.com/m/product/385544
Fall of Vecna
https://www.dmsguild.com/m/product/421754
Reign of Rot
https://www.dmsguild.com/m/product/450868
Wrath of Zuggtmoy
https://www.dmsguild.com/m/product/468752
This team puts out some epic content, and I would love to see their take on a Doomed Golarion where every major AP was failed, resulting in an increasingly hopeless setting.
Plus, they will probably let us fight The Whispering Tyrant (properly, not counting the much maligned heroic sacrifice in Tyrants Grasp), which would be awesome.