Lincoln Hills
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The Fatigued condition is in the CRB, and the various ways it can be imposed (forced marches, resting in medium/heavy armor, hypothermia, heatstroke, recovering from barbarian rage, certain spells, etc.) pop up here and there. In every case, you don't suffer the condition or its associated penalties (which I believe are -2 Str, -2 Dex, and inability to run or charge). Is there some specific question you have about the immunity?
| SlimGauge |
Pathfinder Maps Subscriber
Protects from the Touch of Fatigue cantrip. Some Magi get this added to their spell list (there are ways) and then spam it at low levels with Spellstrike.