
Lithrac |

Magical Lineage - Pick one spell. Drop the metamagic cost by 1.
By itself, it doesn't increase the DC, however if combined with Heightened Spell or Focused Spell, it will.

Halfling Barbarian |

There is that, but I'm looking to go solo here as much as possible. I'm testing this build against the beastmas thread for an upcoming game where my wizard is looking to be able to take out anyone or anything in the way of his goals (including other PCs if necessary). Basically he needs to be able to handle any situation with no more than one or two spells, often lethally.

Dark Netwerk |

If you're high enough level and have a specific spell in mind, Spell Perfection doubles the bonuses granted from other feats (e.g. Spell Focus, etc.) for that spell (it also allows you to ignore the cost of a Metamagic feat as long as it wouldn't bring the spell past 9th level).
Persistent Spell metamagic makes them have to save twice to avoid the effect.
A one-level dip into Sorcerer (Arcane Bloodline) gives +1 DC to any metamagiced spell (assuming it went up by at least 1 level). There are other bloodlines that add DCs to specific descriptors or circumstances (e.g. Boreal=cold, Deep Earth=being underground, Fey=compulsion, Infernal=charm, Kobold=flat footed opponent, Stormborn=electricity/sonic)
Greater Eldritch Heritage (Arcane) at 17th level, if you have the CHA and the earlier feats, adds +2 DC to spells from a single school that stacks with the Focus feats. Or Improved Eldritch Heritage (Maestro) at 11th level, adds +1 DC to language dependent spells.
If the spell has an elemental descriptor of some sort, Elemental Focus and Greater Elemental Focus will work.
There are plenty of spells you could cast "quickened" before your main spell to give the opponent (if they fail any save related to that spell) a penalty on their saves (Bestow Curse, Mind Fog, etc.).

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Precociou Spellcaster trait raises the CL for two specific spells, one of them a cantrip, the other 1st level.
I believe there is an Ioun stone that raises the user's CL in general.
Persistent metamagic.
Mind fog or some such spell, that lowers the target's save by 10, IIRC, if they fail the save against the effect.
If you go with a familiar, a wand of misfortune, I think it is.
If you can afford it, Toppling, Dazing, Rime, or other metamagic that adds a condition to the normal spell effect, when applicable.
As mentioned Spell Focus, Greater Spell Focus, maybe Elemental Focus, if applicable.
Spells that don't allow saves can be good, if you can reliably use them.