It seems like the craftable poisons listed in the main PF book all have DCs that are rather low for mid- to high-level play. For a class like the assassin or alchemist that will use poison a lot, how can poison be kept as a viable tool against creatures with higher Fort saves?
Debuff your opponent first. The Prayer spell & the Intimidate skill come to mind as readily available.
I have come across this problem and you can change the DC that is needed or make up a poison. Also, area affect traps work great as you just need to walk in or be in the area for a trap work. Once I upgraded the poison DC's it was a flood of endless whining ensued. If players can't steam roll something they get upset and quick! Hope that helps...
Thanks for the responses. I'll be playing as an alchemist, and while I can use the concentrate poison discovery to boost the DC by 2, I won't have any other debuffs to sue against opponents.
IIRC there are going to be a host of new poisons coming in Ultimate Equipment. Might be some of those will have higher DCs.