
Tom Sampson |
Alchemical weapons are weapons, and you can poison weapons. That is all legal, per RAW. However, as per the damage reduction rules, I would rule that if your weapon does not do damage, it does not apply an injury poison (so the poison would be wasted).
There will be table variation the rest of the way but it is also reasonable to rule that acid flasks, alchemist's fire, and similar items are not really injuring the target with the glass container whose exterior you poisoned but rather its alchemical contents, and therefore those items would not suffice to apply a poison either, unless your GM permits you to throw them as fragile improvised weapons against normal (not touch) AC, in which case you can get the regular damage from throwing a weapon, the poison damage, and the alchemical weapon's effect if it hits (however, there is a -4 attack penalty for throwing it as an improvised weapon, unless you have Throw Anything or similar - or you are launching it with Telekinetic Projectile). Personally I would allow that, and I would still have the splash weapon function as normal (no throwing damage, no poison) if the attack hits touch AC but not normal AC, but I would, utilizing GM discretion, make you take a -2 circumstance penalty for purposes of resolving if it hits touch AC (but not normal AC - and if it hits normal AC it obviously touches) if you threw it as an improvised weapon. Mixing a poison with the contents of an alchemical vial should also be a non-option owing to alchemical reactions, or require some kind of craft (alchemy) check.
If you want to make a touch attack that poisons enemies, you can just poison bullets and use firearms or just use the Named Bullet spell to make a thrown weapon work against touch AC.

Mysterious Stranger |

What alchemical weapon are you trying to add poison to? Adding poison to something like acid is not going to work; because the acid would dissolve the poison before it it could take effect. Alchemical fire would burn it away when it ignites.
You might be able to create an alchemical weapon that also has a poison effect. But simply pouring a dose of poison into the alchemical weapon is not going to work.

Mysterious Stranger |

Many of those seem to activate when the substance is exposed to air. Since it is the substance itself that causes the effect adding poison to the container is not likely to work. That is going to make adding a dose of poison to such a weapon nearly impossible. When you open the container of the alchemical weapon it will trigger the weapon.
What can probably do is to make an alchemical weapon with the poison already in it. The type of poison used will also have to fit the alchemical weapon. Contact poison will work with something that has a delivery method that actually makes contact with the target. Shard Gel and Pellet Grenades will probably work with contact poison. For something like a Burst Jar, you probably need an inhaled poison.