Interested in any sort of precedent for how it might be different, whether it's an actual rules decision somewhere or even just an anecdote from a Pathfinder novel. In absence of that, I'd jsut liek to know what people think.
Would the creature "feel" the spell being cast on it and wake up?
Can verbal components be done quietly enough to avoid waking a sleeping creature?
#2 is a simple perception check DC0 +10 because asleep +1/10' away the caster is.