| Schraubstock |
Serpenfolk is one of the few humanoids that is immune to "mind-affecting effects" (Bestiary 2). In the Pathfinder Cronicles "Into The Darkness" Serpenfolk was originally described as immune to "mind-affecting magic". Demoralize with the intimidate skill is a non-magical mind-affecting fear effect.
The first one would not allow the use of the intimidate skill, the second does. Is it possible to demoralize serpentfolk?
Imbicatus
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No, Immunity to Mind-effecting includes all uses of mind-effecting including demoralize. You can't demoralize serpentfolk.
Also, "effect" and "descriptor" are sometimes used interchangeably. Even if is said descriptor or magic, intimidate still wouldn't work.