Looking over the Feat lines for bows and crossbows, it appears the crossbow style of combat requires too many Feats to be effective. Are there any unique tricks besides the Feats to make a crossbow more worthwhile? The advantages I see is the higher base damage and increased critical range. Howevever, with Vital Strike being useless with other neat crossbow feats I don't see how to differentiate it other than an inferior option.
Nope.
Does Bull's Eye Shot work with Vital Strike at all?
Does Bull's Eye Shot work with Vital Strike at all?
Yes.