I was looking at Ultimate Campaign today and realized that Seoni's mole is on the wrong side of her face. In the Core book (see Sorcerer picture), it is on her left side, and in the Ultimate Campaign it is on her right. I have not checked other books, but those two I am sure of. I have seen other characters with moles as well. Ameiko from the Rise of the Runelords has one, and I think that half-orc Inquisitor has one IIRC.
So are these moles like in Austin Powers, where they move on their own? Or are they magical devices? Could a witch have a mole as her familiar? Then again, that might be a wart on the nose instead.
What should an enchanted mole be able to do? Maybe they are just odd facial piercings.