If I could change one thing about Pathfinder RPG, it would be to nix Save or Die spells. IMO, they are a "you lose" mechanisms, which I don't think have a place in heroic fantasy.
I took my inspiration from that thread and a comment by Tarren Dei's comment in the original thread: This thread has just been voted "Most likely to spin-off into several satirical off-topic forum discussion threads".