As somebody who absolutely loved Iron Gods and who's group pretty much finished it as it was coming out a couple years back. Hell, Minor spoiler. At the end of Iron Gods we essentially decided to go Star Trek and seek out new worlds and all that junk backtracking the Divinity's crash on Golarion to find a certain important npc's home planet and get her home.
I guess exploration, Interesting places,Cool NPC's and awesome monsters ( I can't get over the idea of demons with chainguns) great adventure hooks, just really taking advantage of the sci-fi setting and how big the universe is for all kinds of zany hijinks. Kind of a Star Wars/Mass Effect feel would be what I would really crave. Mixing in Magic and High Tech and having them both feel just as valid.
What I felt was Iron God's strongest part was it's trilogy setup. Books 1 & 2 showed a strong narrative collection that bridged them seamlessly. Followed by 3 & 4 and finally 5 &6. Having an entire plot thread spanning over two books and handled fantastically was a welcome change from the single book plots and adventures in previous Ap's.
I might be rambling but just like-Really don't just make it Pathfinder In Space! Don't do what you guys did with the high level Demons on the Moon Module. Take full advantage, make it your own and tell a great story that cannot be told on Golarion.