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Pg. 5 - Sure-Handed Alchemy feat
The benefit paragraph for this feat says the following:
When attempting Craft (alchemy) checks to create items using spontaneous alchemy, you gain a cumulative +1 circumstance bonus for each distinct reagent called for by the recipe. A failed Craft (alchemy) check results in a mishap only on a natural 1. Finally, you take no penalties on Craft (alchemy) checks when using improvised equipment to create items using spontaneous alchemy.
Emphasis mine above. The bolded sentence should probably be changed to say that the failed roll only applies if the natural 1 would have fallen within the "failed by 5 or more" threshold, since skill checks don't "auto-fail". Otherwise a 1 would cause a mishap on a result of 4 or less from the DC, which wouldn't happen if you DIDN'T possess this feat.
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Pg. 25 - Tea of transference
This is technically a house rule, but judging by what the item does, it seems reasonable to make the following change to have it compatible with classes that were released in books published after the Alchemy Manual was published.
Add the following to the list of those class features whose uses can be replenished by drinking this tea and converting 1 ki point:
* 1 arcane reservoir point
* 1 inspiration point
* 2 rounds of raging song
* 1 panache point
* 1 phrenic pool point
Likewise, in the second sentence of its description, change "one use of smite evil" to "one use of smite good or smite evil" so that it's compatible with antipaladins as well.
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Pg. 26 - Artokus's fire
This item says it functions like alchemist's fire, which means on the round following the one the target took direct hit damage, they'd take another 1d6 points of fire damage. It's uncertain if the mythic rules for this item means they'd take that 1d6 fire again on the round after, IN ADDITION to 1d4 fire, or if the 1d4 replaces the 1d6 (and the benefit is that the 1d4 potentially repeats over additional rounds). I'm inclined to believe that on the round following the direct hit, both the 1d6 and 1d4 damages occur.
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Pg. 27 - Suffocating powder
Suffocating powder says it produces a suffocating effect, but it's unclear if the actual rules for suffocation are supposed to be implemented, or if not being able to talk is the powder's only accomplishment on paper. If it's the former, this presents a number of problems, which I've gone into greater length in my post on the rules forum.