Title says it all
I have some odd characters sit at my table of the years and some are just so memorable.
Howls-in-High-Pitch - Werewolf the Apocolypse - due to several bad rolls ended up a gelding and just sort of went with it and played it up.
Nude Fighter - Human Monk style after a luchre libre wrestler - The player would actually wear a mask and was very good at getting into character. Played with him at Neoncon 2010 at a couple tables I was GM.
Hidesous Mody the Abortive Midwife - Dwarven Staff Magus - enough said...