Definitely no epic spell seeds. That was horrendous. I'd like for casters to continue receiving spell slots for spells augmented by meta-magic feats. I mean when a 30th level wizard could have a more than a few 9th, 8th and 7th level spells maxed out with just about every conceivable meta-magic feat, that's quite epic enough.
I'm also somewhat fond of a 4e epic destiny concept instead of some sort of epic prc. Logan Bonner wrote a very good article for wizards.com three years ago converting the ED concept over to 3.5. It was too heavy on the immortality side but the basic idea was sound.
To be honest if they just have a basic framework for above 20 play and let us fill in the rest, I'd be satisfied.