One of my players decided to come up with this feat.
Shaped Splash
Prerequisites:Base Attack Bonus +1
Benefit: You can choose not to deal splash damage to specified creatures that occupy spaces adjacent to your main target.
I decided to take it and allow it for use in my campaign with a Alchemist and it turned out rather well. It solved a lot of the playtesting issues we've had with hitting party members. I don't know if it should be just left as a feat for all races, or made a discovery, or even a bonus feat at low level for the class in general. Either way, it definitely helped, a lot.