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Huh. Spoilering my answer since it does mention some in-game stuff.
** spoiler omitted **
Sorry about the confusion, all!
I actually ended up using Blackfrost as a budding plague in Egede to spice it up a bit and imprint the threat of Osoyo breaking loose. I gave the players some good items to help deal with it once they established some rapport in the city. Alas, a player did end up succumbing to the blackfrost which made for an interesting encounter. Irresponsible use of it maybe, but the player was very interested in the scenario for RP reasons so it ended up ok.
I don't recommend it for groups with big attachments to their characters, but if it sounds interesting might be worth scaling back the curse so they can deal with it. This AP is pretty deadly as is.
Kinda wish Blackfrost was in every part of the AP.