Right, so I've been thinking about the whole 'Points of Light' campaign as outlined by WOTC for 4th edition and I had a thought - Savage Tide 'Points of Light' campaign.
The heroes failed. Suddenly the world was hit by the savage tide. All the major cities were affected and the spill over of savage creatures destroyed or seriously affected almost ever bastion of civilization.
The vast majority of high level NPC were overcome either by the savage tide itself or trying to hold back the waves of savage creatures that resulted.
Those high level figures left alive tend to be at best uncaring enough to have stood aside and let civilization fall or at worst, those evil enough to have seen the potential benefits of the savage tide.
Next generation. The wave of savage creatures has ebbed. The reminants of once mighty nations are starting to explore the world again. A world filled with monsters and left over ruins of the past.
How does this idea sound for a 'Points of Light' campaign?