I am big on 5 players in case one cant show due to real life.
To make up partly for that, I would always, always do a 20 point
buy and if you are planing on Mythic anything, 25 point buy would
be needed.
Been playing DnD since 1978 when Chainmail came out.
When your PC's are to week due to there abilities, you
can always downgrade your bad guys. I prefer to have PC's
with higher abilities so I can upgrade my mobs when called
for.
Just saying.