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There have been many POWERFUL villains I have run over the years, but as far as memorable, well that award would have to go Harver "The Carver".
The players had just broken a good friend out of the local jail, but in doing so had also broken out every other convict at the same time. To make matters worse, they came to learn that the small town's overly-fortified prison was just a layover point for the worst-of-the-worst criminals of the region before they were shipped to the capital city where they would be publicly executed. Guilt-ridden, they contacted the local Lord, and confessed their involvement.
The Lord, both livid at their actions and impressed by their honesty, informed them that the town constabulary would round up the lesser criminals, but it was up to them to deal with the most dangerous ones. Three serial killers were among their ranks; Razah "The Canibal", who was said to be raised by wild beasts. He savagely stalked and ate his victims. Lazlo "The Butcher", a monster known for skinning his victims alive. His true identity has never really been known, since he was able to wear a person's face at will (Skin stealer with levels of Assassin). The other was meant to be just a quick distraction but became so much more; Harver "The Carver". This grandfatherly dwarf was said to be discovered in a shack with countless body parts, which he was performing all manner of experiment on. The Lord gave them info in each and sent them after the three and bring them back, dead or alive.
After the first night, the players returned to the Lord's manor with the head of the cannibal, though they were pretty beat up. Since they had expended all their healing during the fight, the Lord offered to send for a healer. Once everyone got comfortable in their separate rooms, an kindly dwarf with a doctor's bag arrived, binding their wounds with bandages and ointments while keeping to lighthearted conversation. At the end he pulled out a syringe with a healing potion mixed with a mild sedative to help them get some rest. I had each PC roll a perception check to notice the bloodstains around the rolled up cuffs of the dwarf's shirt. They rolled sense motive checks to see if this guy was on the level. Amazingly they failed both in spectacular fashion. As they drifted off to medically induced slumber time, the last words they heard were "I can't wait to get you open..."
When they awoke, they were in the basement of the manor, bound to tables. Harver had run a gambit of experiments on them over the past week, up to and including; replacing the dwarf paladin's heart with that of a troll's (giving him a short burst of regeneration if he hit 0 hp 1/day), replacing the catfolk oracles hair with live snakes (just on the head. They gave her 360 degrees of vision), turning the half-drow rogue permanently invisible (which was sort of driving him insane, as per the spell), and partially fused the magus with an ooze (which gave him light fortification and the ability to never be flanked). He had also apparently killed the Lord, his servants, and the original healer the lord sent for.
They players managed to escape, and chased the mad doctor through the labyrinthine basement until they finally trapped him in the wine cellar. After rendering Harver unconscious, they strapped the dwarf to one of the tables with a full waterskin close at hand and had intended to leave him to waste away, alone. The magus had other ideas and beheaded the fiend the moment everyone left the room.
The characters never spoke of what happened in that manor again, but the players still talk about crazy Harver to this day, years later, hoping that somehow the mad alchemist rises from the grave to experiment again.

Salutations fellow dice-jockies! A friend of mine has recently decided that he wants to run a game set in Arcadia in good o'le Galorian. He wants us to be villains in the employ of a mythic black dragon. Ever the helpful PC I asked him what he needed, and his exact words were "An arcane cannon would be good".
After spending a week thinking about it, I got nowhere. I am tapped out of ideas, so I turn to you guys. What could I do to be one of Galorian's more sinister villains?
According to him, things like the Drow Noble are acceptable as first level characters. We're level 10, with two mythic tiers, and our stats are an array; 13, 14, 15, 16, 17, 18.
So far the party is comprised of...
A Graveknight
A Tiefling Bloodrager
An Android Alchemist (Vivisectionist)
And a Corpse Collector (Yes. Really.)
I'd thought about a Wizard/Cleric/Mystic Theurge, or some manner of blasting Sorcerer. What do you guys think?

Ah, the hold shock-n-stein build. I played one of these once, and as such I would highly suggest the Ring of Wizardry I. I used this to devastating effect before.
Another option to look at would be pearls of power. Cheap, easy to carry, and useful in case you should happen to nova on something, and your GM brings out one extra special challenge just cause, though the wayfinder is just all kinds of useful.
How's your AC looking?

YEEEEEEEEEEEEEEEEEEEEAAAAAAAAAAAAAAAHH!!!

I am passing the reins of DMhood off to a player in my Monday night group, and I want to go out with a bang, with a few memorable encounters designed to be both fun, challenging, and just plain wrong.

One such encounter involves the PCs ascending a tower to stop the assassination of their friend as he ascends to godhood. (It's gotten a little high powered.) They will come to a level of the tower that is little more than a steel-grate floor. The trap, when sprung, is a Shocking Floor Trap (+9 to attack, dealing 4d6 electrical damage each round for 1d6 rounds). What I want, ideally, is an enemy in the room that is bolstered by electricity, but I cannot for the life of me remember what creatures are.

The party consists of a Magus, a Summoner, a Rogue, and a Druid, each level 9, each with 3 mythic tiers, so they can handle some punishment. Does anyone have any suggestions?

One idea I've thrown around in my head is an Orc who has made a deal with demons for the promise of more power than any Orc warlord before him. In exchange he has promised whatever demon lord he has pledged himself to a ridiculous number of souls, and to do that he required a large number of sacrifices, which means a lot of nasty evil priests.
This Orc is cagy, and more cunning than his kin. He devised a way to turn his army into a roving horde of rampaging demonic priests. Their "right of passage" is an elaborate ritual that completes with a sacrifice, and an oath of fealty in a language that the Warlord calls "true orc" (Abyssal). Their weapons are blessed by the Warlord's high priests (either demons in disguise, or Orc shaman in on the real scope of what's happening.)
To build this army, he either murdered (by his own hand, or through another) all of the various leaders of the surrounding Orc tribes. He then consolidated his power and took them over one-by-one, crushing any opposition.
As far as crunch goes, I imagine a Bloodrager from the Advanced Class Guide with the Abyssal bloodline. He'd be potent on the battlefield, and if you need to give him an extra boost, there are quite a few Demon Lords that hand out some pretty scary boons. With the amount of sacrifices he's making, demons will be begging to court him. He might even be made into a half-fiend.

189. The Fancy Lads
190. Killa-Creature Inc.
191. Masters of Disaster
192. The Lords of the Broken Chest
193. Vindicated Incorporated