You might first think that it's unrealistic, but hear me out. Diamond Lake is about three days from the Free City. If you run this in Eberron, it is assumed that Sharn's your big city. But I have a slight problem with this: Breland is supposed to be relatively safe. I mean, a lizardfolk tribe in a swamp in the middle of Breland, where Diamond Lake is supposed to be according to Keith Baker? Ridiculous, I say. That's the problem with most of Khorvaire. It's simply too safe.
Now consider this. Use a larger version of Stormreach as the Free City. RickVigorous from the WOTC boards actually statted up a Stormreach of about 11,000 in population. If you make the assumption that there are smaller towns and villages around Stormreach, then you have a basis for doing AoW there.
IMC, I actually have an independent nation of about 40,000 on Xen'drik called New Breland, of which Stormreach is the capital. New Breland was the first and only colony on Xen'drik and became a neutral sovereign nation during the Last War. It is much wilder than the main continent, and therefore IMO more suited to run this AP.
Granted, I still may run this thing in Sharn/Breland, for ease of play. But I must be honest, the thrill of a wilder environment (sahaguin, giants and drow anyone?) is appealing. Thoughts?