Prebuffing against onset saves such as disease.

[Ataraxias]

Can someone clarify if buffing right before a save against the onset of a disease, or temporary negative level can be done?

I recently heard the argument that you'd need to have those sort of effects in place for the duration of time leading up to the save for it to count, so a Bear's Endurance would need to last 24 hours to work for a save against a disease for a 1 day onset.

Is this correct?

[blahpers]

That's an interesting argument, but it's a house rule. AFAIK, nothing states that you have to have the bonus for the entire interval.

[toastedamphibian]

It's the way everyone seems to run crafting...

But see Antiplauge: Alchemical item that give a bonus to saves against disease for 1 hour. It also lets you roll twice if already infected. So intent seems to be that a 1 hour bonus is sufficient to help.
(50gp, craft dc 25)

Also make sure someone makes a heal skill check vs the save dc. Only takes 10 minutes and gives +4 on their save for the day.

[Cevah]

Check out the spell Saving Finale.
Check out the items: Four-leaf Clover, Fortunate Charm.

Rerolls and bonuses to saves.

/cevah

[maouse]

If you take a cure before it kills you do you still die? No. You are cured. So if you take a partial fix right before it kills you, are you partially fixed? yep.

Real life example: having a mint before your breath kills someone else. Food's still stuck in your teeth, but your breath smells minty clean. Cured of halitosis? Nope. But you got an added modifier until it works its way out or you cure it (brush your teeth!).