My players finished In Hell's Bright Shadow last week. We start Turn of the Torrent tomorrow night, but I'm going to let them have a bit of a break so that they can get to know Kintargo and get some better equipment. After a certain point, I'll have the Ninth Proclamation be announced via a town crier. A day or two after that is when Setrona comes into play.
Given that I've removed the Rebellion rules entirely, I'm going to have it that the PCs hear some scuttlebutt about Setrona being worried about Octavio after the Ninth Proclamation. Hopefully it will be enough to prompt the PCs to head to the Tooth and Nail.