Well I plan on bringing a variation of the WarHammer 40k lore into the universe. One of the adventures I have planned so far is basically Dead Space 1 but with the Death Guard having taken over a ship or station. Players get grav beamed into the hanger and can't leave as the power core of the ship is drained by said grav beam in the process. They then have to set out into the station to find a way to power their core. Slow suspenseful build up, then all out chaos ending in a big ole boss fight with a Nurgle Deamon Prince. Most of the adventure can be done stealthily however combat is inevitable at the end.
Another idea I have going through my head is that the players are going through space and pass through a strange mass of some sort on their way to destination planet. They land planetside and are immediately beset upon by the Imperial Guard who quickly take them into custody. They are captured and knocked out only to be woken up in a chamber within the city they originally were set out to visit. A single space marine acosts them for their mistake, they had flown through an Ork Spore Cloud and the spores had made land fall. They are then tasked to expunge any existence of Ork life or be killed on the spot for Heresy. They are sent out with a contingent of guardsmen with flamers. They have two weeks to eradicate the foes as the nearest battle barge is two weeks out. They then have to set out along the trajectory of their space craft, guardsmen in tow and eliminate all signs or Ork life. Again slow building, first experience with this kind of foe type adventure.