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No, the target may forget they were the target of an assassination, but they would still be immune to it for the rest of the day, since the immunity is not contingent on anything other than making a successful save.
What you could do is walk up to some unsuspecting victim and sneak attack them (they should be flat footed), then cast memory lapse and say "Sir, is that blood on your coat? Are you alright?" then assassinate them as they try to figure out why they're hurt.
Another use of memory lapse would be to walk up to two people, assassinate one, cast memory lapse on the other, and then say "Is your friend hurt? Is there anything I can do to help?" as you assassinate the second person.