I recently developed a fascination for Rice Burroughs' Mars saga and would like to eventually run a game based on this type of science-fantasy universe, like Conan the Barbarian in space. Anyone has any game systems to recommend?
Pathfinder can actually do some of that. Check out Distant Worlds - Golarion's solar system is very heavily based on the pulp sci-fi and sword-and-planet fiction of Burroughs and his ilk.