I am currently finishing up with the second adventure, looking at the third at what I plan on altering and some general advice. If you have players who have specific weapons that are not found in these adventures, alter the loot that is found. One of my players is a ninja, so I an item specifically for his class in one of the items. I am not big on item creation feats (do you want to stay at home and make stuff or adventure?), so I make sure there is something for everyone. If I see an encounter that might be difficult for my party-say an invisible NPC and the party has no way of detecting it, I will drop a scroll in of detect invis.
For the card game-I am going to allow as many players who want to play, play-but for each player-the NPC gets an additional role. I don't want half the party sitting around watching (and why the designers did this, is just plain lazy and foolish).