I have also had some...interesting experiences in my time with the Deck of Many Things. My worst encounter, however was with a Bag of Beans, using the 2nd edition Magic Item Compendium Volumes multiple random charts. Bear in mind I was NOT the DM but a player in this game.
The Party was already full of conflict, in game,not OOC, my Drow Weaponmaster character being the focus of most of it. The party rogue, a halfling thief had gotten a Bag of Beans a little earlier in the adventure , and had decided to plant a bean while we were camped in the wilderness, en route to some baddies castle. The first effect, permanent confusion on the planter. He rolled to drop his held items. This scatter the entire bagfull of magical beans across the area (I'm starting to think the DM was being particularly kooky, as he didn't require these beans to be planted to take effect).
The resting party was next hit by an Ice Storm (bean conjured), we thought we were under attack and began to flee down the mountain path trying to find out assailant. The ground began to rise in a giant 100' column of stone underneath us, to a height of about 200' up I believe. Then a strange magical horse and saddle appears. The character that mounted it (which was really stupid, and believe me I tried in Char to discourage them) was given a one way trip to Gehenna I believe.
We still had NO idea what was really happening. Then the rogue backstabbed the party cleric, the wizard's cloak turned into a rug of smothering, a minor death appears and a round later the column of stone disintigrated (that was part of the proscribed effect). Essentially, total chaos ensued. Thank goodness my Drow could levitate. The rest of the party miraculously, minus the cleric and the now Yugoloth-food Psionicist, survived. It was crazy, but we laughed our butts off when the DM told us what had caused it.