Pathfinder is great, but system fatigue begins weighing me down after a certain point. The wheels still seem to fall off at or just after 12th level, things are too overly codified for my tastes, I feel like there's too much emphasis on min/maxing to "play it the right way", etc.
This is why I'll be giving D&D another chance. I hoping, having taken a lesson from Paizo, that they'll listen to their gamers, and I'm intrigued by the fixes, which I hope to explore more of at GenCon. Rules bloat, the Christmas tree effect, and the insane amount of modifiers deter me in PF, and now that we're at high-level play, there isn't a session that goes by where someone gets lost in the numbers or an obscure rule gets quoted. It's taking away from a greater focus on Role-Play.
It appears the two systems won't be so incompatible that I can't continue to use the APs, which is where I feel PF shines.