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The methods used here are outside my field, but here's my best shot. The math used to calculate the images for the DMRI (diffusion MRI) is beyond me.
The paper's authors used a very specific type of MRI (magnetic resonance imaging - basically a giant electromagnet) that allows for imaging/measuring of neuronal fine-structural as a result of the diffusion of water molecules. Previous studies have found differences in brain white matter in trans individuals versus cisgender, and this study observed a clear pattern in the mean diffusivity (the physical correlation here would be higher white matter density leading to lower diffusivity). They observed cis females with the highest diffusion rate, cis males with the lowest, and trans individuals in between in virtually all white matter regions mapped.
The diffusivity numbers also matched up with the plasma testosterone levels in their bloodstream (I don't have access to the full paper at home, so I don't know if the trans individuals were on HRT or not, which could make a difference here). The study suggests that the observed brain differences are the result of testosterone exposure levels during prenatal development of the fetal brain and possibly the earliest post-natal stage.
He's also done work for Image before, with Witchblade being where I first came across his work. He's also doing his own comic 'Death Vigil', and apparently he's working on a 'teen witchblade' spinoff comic. I have no idea how he manages to sleep with that workload. :D
Ambrosia Slaad wrote:
I'm so looking forward to that one-shot special, and then after that I'm just about dancing because of Stjepan Sejic coming on as their new artist.
I suspect it's an amalgamation of lore from 2e/3e and 4e. In 2e and 3.x, Grazzt was explicitly the child of Pale Night. However 4e used an entirely different cosmology and in-game history, and placed Grazzt as the child of Asmodeus IIRC.
The subtext to suggest the pairing is easy to pick up on, and in some nebulous form it has probably been dancing around for a long time.
To be honest it's a fun idea to suggest that Grazzt was born of a chance meeting on the battlefield of the earliest years of the Blood War, when Pale Night encountered Asmodeus prior to his fall from LN to LE, and that his encounter with her may have been the original trigger of his corruption by Evil. And even if that never happened, even if the story was 100% false, I'm sure that the 'loths would happily whisper it just to put seeds of doubt and confusion into Grazzt and Asmodeus's minds.
If there was a tangent point for Obsession/Despair/Hunger/Agony you'd have the Oinodaemon, at least in my headcanon. :D
But by singling out Islam as inherently political, you're doing just that. Or at least defining fanaticism and political aspirations as outliers in Christianity, but the norm in Islam. Which is very hard to justify historically. Even if it might be the case at this point in time. That doesn't mean it's inherent in the nature of either religion.
I'm curious what exactly you mean by this? Christianity began among the politically marginalized and faced Imperial sanction and suppression up until 311CE and was legalized in 313CE. It took centuries before it had political power and became the Roman state religion in 380CE.
Islam on the other hand (assuming here for the moment the historicity of largely 9th century sources discussing 7th century events) began with the spread of faith by violence and then empire building in the vacuum of collapsing Byzantine and Sassanian power in late antiquity. Among the earliest titles for the Caliph was 'commander of the faithful' with no real difference there between religious authority and secular/military power.
That's a very distinct difference between the two religions.
Ray Vallese wrote:
1) Well now I'm quite glad that I kept the truth of that relationship ambiguous when I wrote up the Marauder in Dragon magazine a few years ago. :)
2) Garak was a great character on DS9. As for A'in, that's largely how I always played him as well, much to my players curiosity and eventual lament. Such a fun character to use.
In 'Faces of Sigil':
1) Did you intend for Kylie the Tout to actually be the Marauder's daughter as implied or just to have the Marauder's protection of her from Autochon be something just to mess with the Bellringer's head?
2) A'kin is indeed just a really friendly shopkeep I assume? ;)
It's called 'The Great Beyond: A Guide to the Multiverse', it just hasn't been updated from the original 3.5 publication to the Pathfinder ruleset formally. But the fluff still describes all of the planes in overview, with later books like the BotD series going into specifics on their area of focus. :)
Also, it should be noted that until very recently, the law required anyone who juridically transitioned should be sterilized (even if there where no medical issues with them getting kids) and any saved eggs/sperm be destroyed
That's an absolute abomination. What was the medical or ethical rationale used to even vaguely attempt to rationalize that? That's horrific. :(
Tarinia Faynrik wrote:
While Lissa and Crystal both gave some pretty comprehensive answers to your question, I'll chip in what I can.
Each of our experiences is going to be unique on some level. The best way that I can relate from my perspective is that it's on some level like phantom limb syndrome in that it feels like portions of my body are missing and things that shouldn't be there are. Looking in a mirror is often jarring and I try to avoid it if at all possible, even if by most standards -and most importantly my spouse's standards- I'd be considered an attractive male.
It's a combination of that gnawing physical perception of things being -off- and then the social perceptions and reactions from other people that likewise register as being wrong. For me at least I very much could care less about other people's perceptions of me, clothing, etc versus just having a body that didn't feel like a costume with a broken zipper so it can't be removed.
Let them know that you want such a book and it might happen. :)
Paizo also knows the extent to which I'd go to contribute to such a book, including no longer bugging the hell out of them at GenCon for that, and buying them all pizza, among others. :D
Marroar Gellantara wrote:
The way I see the transgender experience is that such people have a gender that requires a different physical expression than the intelligible gender sphere our western thought wants to place them in at birth. This way gender is still something core about a person that we should allow them to express, but it does not depend on genders being essentially different. It would also explain why not all transgender individuals require genital surgery or even hormones.
It's becoming increasingly clear from the scientific literature that internal gender identity is neurologically hard coded into brain structure during early fetal development, but due to certain events (likely included an interplay of genes and maternal hormone exposure) specific regions of the brain are masculinized/feminized on a sliding scale, allowing for a very diverse degree of potential internal gender identities, some of which may lead a person to desire to ultimately transition and some of which do not, with a ton of variation thereof.
We're still figuring out everything that's going on, but it's fascinating. It also arguably IMO makes non-emperical theories of gender somewhat irrelevant.
And in Not-Good-News, Republican Congressmen ask Labor Dept. to withdraw the LGBT Protections the Dept. recently set forth.
They're asking for a 60 day public comment period during which the labor dept ruling would not be in effect. I strongly suspect that the two members of Congress behind this may be surprised at how much flak they're going to get from a good chunk of their own party over this. It's rapidly becoming an issue of civil rights that's supporting by people across the political spectrum. This is a good thing. Those railing against equality for LGBT folks are an old and dying breed on both the Left and Right.
James Jacobs wrote:
The feat wasn't written with a weight limit in place, which I'd leave more to DM adjudication than not, as it's less about weight than it is about fine control which the tail lacks in comparison to a full hand. Hold, pick up, and stow objects but not wield weapons, shields, use spell components, etc (though in my home campaign I could personally be persuaded to allow the tail to perform somatic components of spells).
I'm not specifically familiar with this having been accomplished already, but it's conceptually feasible to insert human bone marrow into immunocompromised pigs of some variety and then harvest the resulting blood with appropriate filtration. It seems an engineering problem than anything else.
The problem I would raise on a safety level would be the presence of porcine endogenous retrovirus, which makes any level of xenotransplantation involving porcine origin cells problematic, even if in the case of harvesting RBCs that lack a nucleus.
But beyond that, I suspect that most of the outrage over you know, helping people, was from the 'It isn't natural' anti-biotech fringe minority of the extreme left. Similar outrage from that camp in recent years over human/animal chimeras in research and creating human embryos using genetic material from a third person to cure various diseases caused by mitochondrial dysfunction in the potential child's two primary parents. Sigh. But I'm going on a rant. I'll stop.
I hope that you enjoy it :)
It was intentionally written with as many hooks as possible that don't rely on any particular set of rules to be useful. The monsters that it does have in the back have since all been updated to Pathfinder rules (in Bestiary 2). And if it helps, it was very much inspired by what came before in terms of the planes from AD&D/Planescape, though obviously it's a different IP. Much respect and appreciation for that though.
Ideally IMO an expanded planar source book (hardcover even?) written formally in the Pathfinder rule-set would be great. Would be great to see at some point, but I have no insight into if that's on the horizon or not.
Hmm? Tegresin is just Tegresin. I'm not aware of the name being the same as anything from RL (Ravenloft I assume?). Other than perhaps making him in attitude about as much of a yugoloth as you can find in Pathfinder which has no yugoloths, there wasn't anything more on him as a nod to anything else (more details on him and his demiplane appear in 'Classic Treasures Revisited' in the Well of Many Worlds section.
Just a few lines in 'The Great Beyond'.
James Jacobs wrote:
That's... really really cool. :D
Also this is one of the reasons why Paizo is awesome. Because the Creative Director will show up on the forum and post behind the scenes details about what inspired material that showed up in the game.
I really wish that I could have played in that home campaign of yours James. I also wish that I lived in Washington so I could run for some of you folks (yes, I made my home group cry out of character, I need to spread that kind of DM love around). ;)
The Doomkitten wrote:
It isn't always easy to come to firm grips with that sort of self-realization either one way or the other. I know that I struggled with it for a long time and completely suppressed it for many years.
Not everyone has the same experience here with this. For some people it's easy to answer that question, for others, not so much. I'm not sure if I would have been able to eventually come to terms with my own self-identity if not for my partner talking it out with me and making me realize what I'd been suppressing for so long out of social norms being what they are.
Learn about things, listen to other folks and talk to them and piece it out for yourself. The self-discovery is worthwhile, regardless of the answer that you ultimately give for yourself. Many folks have been down this road before, and know that you're not alone in that. :)
IIRC, there's a female urdefhan illustrated in one of the last sections of Book of the Damned 3, where it briefly discusses urdefhans and other creations of the 4 Horsemen.
James Jacobs wrote:
And they're awesome. :D
So awesome that I've referenced them in at least two products that I worked on. :)
Now I'm going to go feel really cool because someone thought that I came up with one of your concepts.
Jonathon Vining wrote:
There's that allusion as well - that what we know of as the Abyss is potentially just a tangent zone to another reality that's even worse than the Abyss. The Abyss and the Maelstrom are both the only truly infinite of the Outer Sphere planes.
I have very long hair. In fact I have the longest hair at my company. I don't think that having long (well kept) hair has been an issue at interviews, but I do suspect that it -would- be an issue if I didn't have the resume and prior work experience and publications that I have.
Having long hair, piercings, tattoos I suspect is less of an issue once you're already -in- a professional field, but I don't doubt for a second that for entry level jobs yes, it would impact things negatively.
Common cosmology yes. Pharasma judges all souls.
Of course there are suggestions that the infinite depths of the Maelstrom touch upon other realities altogether (with the other planes of the Great Beyond being just one local island of stability, one bubble of foam, one shallow point in the Cerulean Void).
Jessica Price wrote:
Couldn't have been said better.
I've seen a much more diverse pool of players now than I saw when I first started playing RPGs, and I think the industry as a whole -and Paizo as a shining star therein- have made some some real strides in diversifying their audience and in providing games that increasingly reflect that diversity. With that being done, the applicant pool for industry positions will itself become more diverse, and that's a good thing.
A very good friend of mine in college introduced me to RPGs in the first place, and she pushed me to stop writing for myself and submit stuff to Dragon and Dungeon. She's damn talented herself and I pushed her to do the same, but when Dragon magazine stopped being printed she thought that her chances of getting published in the same route that I'd taken to get into the industry died. So I prompted her to enter RPG Superstar, and she did. She didn't make it far, but the opportunity did spur her to continue trying various creative pursuits and she's now doing stuff with Eclipse Phase that's rocking.
Push creative and talented people from every background and group to apply for open positions, take open calls, and talent will rise to the top. :)