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We'll also probably see more Curse spells that make it extremely hard to take off or cure with even high level magic.
Curse magic, particularly with the new curse subtype introduced in (IIRC) Ultimate Magic, is definitely an area that's wide open for further development. Much like haunts, or a Linnorm's death curse, there's some good potential for curses and cursing to be a built in motivation for adventure, and thanks to the Witch class and its hexes, there's a lot more room for PCs to get in on the action and for curses to be more than just the plot choo-choo/McGuffin used to spur the PCs into action and set the 'rules' of this particular scenario.
Some sort of infectious curse mechanic (making it function sort of like a disease), or large area affecting curses (dealt via Incantations or similar processes more involved than 'some 5th level d00d cast a spell), could also be useful for adventure-building.