Thing is - while GMs and players everywhere can tell whatever story they like and have fun in whichever way suits them, surely you'll need to take, at least a few steps back from reality when playing in a game such as this.
Pathfinder isn't really written for super-realism, the laundry list of trouble that would arise from trying to maintain a realistic feel while playing by the rules, is really quite amazing.
Heroes falling off an airship and dropping a clean, uninterrupted 800 ft, before hitting unyielding flagstones. Then stand back up and brushing the dust off.
High-level martials destroying an iron-golem with a soup-ladle.
Characters outrunning horses.
Characters standing in lava.
Characters doing more damage with a chair-leg than a dagger on an equally clean strike.
The worlds greatest archer misses the broad side of a barn 5% of the time.
A character just punched through a solid-oak door.
A character just eviscerated a stone-collumn in 6 seconds flat.
The list goes on, but it seems impractical, to me, to try to reason away everything the system permits. Surely, if you wanted to run realism you could use the Storyteller system or somesuch. I remember Dark-Ages vampire Chronicles I've played in. Combat tended to be over in one or two solid hits.