My hope, and this is wishful thinking, is that an AP will be presented either with advanced players in mind either with the core design or at least a presentation of alternate tactics/rebuild suggestions. I believe alternate statblocks are asking for too much.
My thought here is that Paizo has been experimental in theme and design, so I don't know that an "advanced" AP would be completely out of the question. I realize, from the designer perspective, they are aiming to paint with the broadest brush but I believe there's probably enough for a market out there for an advanced type AP. GMs, like those in this and other threads, can scale up encounters, I believe you could as easily scale down encounters if you ran and advanced AP and your group was having a hard go of it but really liked the story.
I like the MMO type suggestion but it is a slippery slope as most MMO content at that level has a model where success is achieved through multiple attempts. Table top campaigns don't have that luxury of having multiple wipes per an encounter, so you have to be real careful with the scripted mechanics.